The UIC study is the first to find evidence of significant numbers of neural stem cells and newly developing neurons present in the hippocampal tissue of older adults, including those with disorders that affect the hippocampus, which is involved in the formation of memories and in learning. The idea that new neurons continue to form into middle age, let alone past adolescence, is controversial, as previous studies have shown conflicting results.
They publish their results in the journal Cell Stem Cell. The study provides evidence that this occurs even in people with cognitive impairment and Alzheimer’s disease, although neurogenesis is significantly reduced in these people compared to older adults with normal cognitive functioning.
In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age. New neurons continue to be formed in the hippocampus into the tenth decade of life, even in people with mild cognitive impairment and Alzheimer’s disease (Illustration: Orly Lazarov, et al.)
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